What Is A NT-pro BNP Test?
NT-pro BNP (N-terminal pro B-type Natriuretic Peptide) test is a blood test that measures the levels of NT-Pro BNP peptide in the blood stream. The peptide is released by the heart when it is in stress and strain, particularly when the heart is struggling in pumping blood effectively. High NT-pro BNP levels indicate heart failure or when the heart is overworked or damaged. The test is primarily used to diagnose heart failure, assess severity of heart failure and monitor effectiveness of any ongoing treatment.
The test is also used to distinguish heart failure from other conditions that cause similar symptoms such as shortness of breath and fatigue. Doctors use NT-pro BNP test as a valuable tool for guiding treatment decisions and improving patient outcomes in patients with heart disease.
How is the Test Performed?
Preparation
This test requires a blood sample. No special preparation is needed for this test.
Sample Collection
A healthcare professional draws a blood sample which is sent to a laboratory.
Lab Analysis
The blood sample is tested using immunoassay techniques to measure the concentration of NT-pro BNP peptide.
Result
Results are usually available within 24 hours.
What are the symptoms that prompt this test?
The NT-pro BNP test is often ordered when a patient exhibits symptoms of heart failure or has risk factors for heart diseases. Common symptoms include:
Adults
- Shortness of breath
- Swelling in the legs, ankles or feet
- Fatigue or weakness
- Rapid weight gain due to fluid retention
- Frequent urination at night
- Irregular or rapid heartbeat
Children
- Difficulty breathing
- Poor appetite or failure to thrive
- Frequent coughing or wheezing
- Increased sweating, especially during feeding (in infants)
- Reduced ability to exercise or perform physical activities
What are Normal Ranges for This Test?
The normal ranges of NT-pro BNP vary according to age. General guidelines are:
Individuals below the age of 75 –120 pg/mL
Individuals above the age of 75 – 450 pg/mL
**The above mentioned range is for information purpose only. Normal levels are dependent on a number of factors including age, gender, testing method and health condition of patient etc. Result interpretation should be done by a qualified doctor or healthcare professional.**
What Happens if Test Results Show Abnormal Levels?
If NT-Pro BNP levels are higher than normal, it may indicate heart failure, acute coronary syndrome or other heart conditions. Depending on the results your doctor may recommend:
Additional Test – Echocardiogram, Electrocardiogram (ECG) or cardiac MRI.
Medical Management – Lifestyle changes, Dietary changes, Medications, Therapies or specialized treatments.
Referral To A Specialist – In some severe cases, referral to a cardiologist for further evaluation and treatment.
Hospitalization might be required in severe cases to keep patients under observations and keep track of the medication/therapy outcome.
