17-OH Progesterone Test

Accurate hormonal analysis for better health. Get crucial insights about your body’s functioning.

What is 17 OH Progesterone?

17 OH Progesterone (17-hydroxyprogesterone) is an endogenous steroid hormone involved in the synthesis of cortisol and androgens which is produced in the adrenal glands and to a lesser extent, in the ovaries and testes. It plays a crucial role in production of cortisol, another hormone that helps regulate metabolism, immune response and manages stress. Abnormal levels of 17 OH Progesterone often leads to certain health conditions, particularly Congenital Adrenal Hyperplasia (CAH), a genetic disorder that affects cortisol production in the body.

How is the Test Performed?

17-OH Progesterone test is conducted through a simple blood draw, usually taken in the morning when body’s hormone levels are the most stable. The sample is analyzed using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), ensuring high accuracy. Patients are advised to avoid biotin supplements 24 hours before the test to avoid interference with the hormone levels.

What are symptoms that prompt this test?

Your healthcare provider might warrant a test when you have symptoms that suggest abnormalities in adrenal gland function, particularly CAH which is a genetic disorder that affects the adrenal glands’ ability to produce cortisol and aldosterone, leading to excess production of androgens. Here are some symptoms that might prompt this test:

Newborns

  • Symptoms in newborns can include genitalia that are not clearly male or female
  • Severe dehydration
  • Vomiting
  • Low blood pressure

 Adolescents

  • Signs of early puberty
  • Growth spurts
  • Excessive acne in both boys and girls
  • Excessive hair growth in girls
  • Deepening of voice in girls
  • Increased muscle mass and weight gain in girls

Adult Women

  • Irregular menstrual cycles
  • Infertility
  • Excessive hair growth
  • Thinning of hair on head

 Adult Men

  • Low sperm count
  • Infertility

What are Normal Ranges for This Test?

The normal ranges for this hormone can vary based on age, sex and time of the day the test is performed. The general accepted normal ranges are:

  • Infants – Less than 630 ng/dL (nanograms per deciliter) after birth with levels decreasing after first few days.
  • Children (pre puberty) – Less than 110 ng/dL for male and less than 100 ng/dL for females.
  • Adult Women – Less than 285 ng/dL for pre-menopausal women and less than 51 ng/dL for postmenopausal women.
  • Adult Men – Less than 220 ng/dL for males.

**The ranges may vary depending on the assay of test, time of day when sample was collected.**

What Happens if Test Results Show Abnormal Levels?

Abnormal levels of 17 OH Progesterone, particularly elevated levels, can indicate Congenital Adrenal Hyperplasia (CAH) or other adrenal disorders. Typically your healthcare provider might demand further testing to confirm diagnosis and assess the severity of your condition. These tests might include genetic testing, imaging studies of the adrenal glands etc.

  • If CAH is diagnosed, treatment often involves hormone replacement therapy to correct the imbalance of cortisol and aldosterone.
  • Ongoing monitoring for individuals diagnosed with CAH or other adrenal gland disorders is necessary to ensure hormonal balance.
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Why Choose Genex Lab 17-OH Progesterone Test

State Of The Art Technology

We use advanced technology and equipment to ensure precise and reliable results. Our cutting-edge tools and methodologies guarantee the highest standards of lab testing.

Highly Skilled Team

Our team consists of skilled technicians trained to handle complex hormonal tests with high accuracy. Each member has years of experience & specialized knowledge to every test.

Fast Turnaround Time

Get your results quickly, helping to make timely decisions regarding your health. We understand the importance of prompt information for effective health management.

Patient-Centered Care

Genex Lab prioritizes your comfort and satisfaction throughout the testing process. Our compassionate approach ensures a supportive and reassuring experience for patients.

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