ANA Profile
Detect autoimmune disorders through our ANA screening with highly advanced technology and techniques.
Disease.
Autoimmune Disease Tests
Department.
Immunology
TAT.
7 – 9 Days
Sample Type
- 2 mL (1 mL min.) serum from 1 SST
What is ANA Profile?
The anti-nuclear antibody is produced in the body by the immune system against the tissues of the body. The anti-nuclear antibody attacks the nucleus of the body’s own cells thus acting as an important indicator of an autoimmune disorder.
ANA screening is a blood test that detects the concentration and pattern of antinucleus antibodies present in the blood. It is a vital diagnostic tool in the detection of autoimmune disorders like systemic lupus erythematosus (SLE), Sjögren’s Syndrome, Rheumatoid Arthritis, and other disorders. A positive ANA test does not confirm the presence of an autoimmune disorder and may require further testing as it is the first step in the diagnosis of autoimmune disorders.
How is the Test Performed?
Antinuclear antibody screening is a straightforward and minimally invasive blood test that provides fast and reliable results for the diagnosis of autoimmune disorders;
Preparation
- No preparation is required for the ANA screening.
- Fasting is normally not required for this test.
- You must inform your healthcare professional if you are taking any medication.
Collection
- A trained phlebotomist draws blood from the vein typically from the arm, some people may experience a stinging sensation for a few minutes.
- The sample is then placed in a chemically treated tube.
Laboratory Analysis
- The sample is sent to the laboratory for analysis.
- The expert lab technician analyzes the sample using techniques like Indirect Immunofluorescence or enzyme-linked immunoassay.
What are the symptoms that prompt this test?
ANA screening is typically referred to people experiencing the following symptoms for early diagnosis and treatment of the disease;
General symptoms
- Persistent unexplainable fever
- Hair loss or hair thinning; alopecia
- Butterfly-shaped rashes on face and nose that worsen with sun exposure
- Tingling or numbness in hands and feet indicating the involvement of the nerves
- Photosensitivity; sensitivity to sunlight leading to rashes and burns
- Unexplained pain and tenderness in muscles
- Weakness
- Fatigue that is not relieved by rest
- Abdominal pain indicative of an intestinal or pancreatic disorder
- Swollen glands associated with autoimmune disorders like enlargement of lymph node
What are Normal Ranges for This Test?
ANA screening results are given in titers i.e. the concentration of antinuclear antibody present in the blood and the patterns. The generally accepted reference range is given below;
- Negative – below 1:40
- Positive – above 1:40
**The reference range for ANA screening is controversial and varies between laboratories. The above-mentioned values are for general guidelines only. Your healthcare provider will provide the correct interpretation of the result.**
What Happens if Test Results Show Abnormal Levels?
Abnormal results of ANA screening suggest that the person might be affected by the following conditions;
High ANA Levels indicate
- Overactive immune system
- Lupus
- Thyroid disorder
- Liver disease
Low ANA Levels indicate
- Low levels are not significant and found in healthy individuals
Additional tests are suggested by the doctor for the confirmation of the disease. These tests include;
- Anti-dsDNA
- Anti-Smith
- Anti-SSA/SSB
- Imaging studies like x-rays or MRIs
After the confirmation of the disease, your healthcare provider will start disease-specific medication along with dietary and lifestyle changes with regular monitoring to ensure effective treatment.
Why Choose Genex?
State Of The Art Technology
We use advanced technology and equipment to ensure precise and reliable results. Our cutting-edge tools and methodologies guarantee the highest standards of lab testing.
Highly Skilled Team
Our team consists of skilled technicians trained to handle complex hormonal tests with high accuracy. Each member has years of experience & specialized knowledge to every test.
Fast Turnaround Time
Get your results quickly, helping to make timely decisions regarding your health. We understand the importance of prompt information for effective health management.
Patient-Centered Care
Genex Lab prioritizes your comfort and satisfaction throughout the testing process. Our compassionate approach ensures a supportive and reassuring experience for patients.
Related Tests
- Anti Double strand DNA (ds DNA antibody), Qualitative
- Complement C3
- Complement C4
- Rheumatoid Factor (RA factor)
- C Reactive Protein (CRP)
- Erythrocyte Sedimentation Rate (ESR)
- Thyroperoxidase (Anti-TPO) / Anti Microsomal Antibodies
- Thyroglobulin (TG)
- Urine Analysis/ Routine